Job Title

Scientist (R3)

Job Description

Org Marketing Statement
All over the world, Pfizer colleagues are working together to positively impact health for everyone, everywhere. Each position at Pfizer touches and contributes to the success of our business and our world. That’s why, as one of the global leaders in the biopharmaceutical industry, Pfizer is committed to seeking out inspired new talent who share our core values and mission of making the world a healthier place.

Role Description
At Rinat, we are dedicated to developing new protein-based therapeutics to improve human life. We use the latest scientific knowledge and apply novel approaches to discover new ways of treating disease. We encourage cooperation and support a high level of scientific freedom to find the best answers to biological questions. Rinat was formed in 2001 as an independent, private biotech company. In 2006, we were acquired by Pfizer, and now work as an integral part of Pfizer’s mission of working together for a healthier world. Located in South San Francisco, Rinat provides the feel of a small start-up company with the resources of a large pharmaceutical company in the heart of the biotech capital of the world.

Responsibilities
We are seeking a highly motivated senior research associate to join our efforts in discovery and development of novel cancer therapeutics. The successful candidate will use a wide range of techniques to characterize potential tumor targets and to develop therapeutic approaches. Major responsibilities will include experimental design and execution to evaluate drug candidates with both in vitro assays and preclinical animal models, and to present study results in group discussions and team meetings.

Qualifications
•BS/MSc in cell biology, cancer biology, immunology or related disciplines with >10 years laboratory experience, training in the biopharmaceutical industry or academic institutions.

•Broad knowledge in the fields of oncology and cell biology. Experience in cancer immunotherapy drug discovery is a plus.

•Excellence in tissue culture techniques is a must. Hands on experience in primary immune cell culture, generation of stable and transiently transfected cell lines is strongly preferred.

•Comprehensive knowledge in developing and executing cell-based assays including (but not limited to) ADCC, CDC, proliferation, apoptosis and various cytotoxicity assays is required.

•Extensive experience in basic immunology techniques such as flow cytometry and cytokine analysis with applications on antibody screening and characterization.
•Proficiency with molecular biological techniques such as primer design, PCR, plasmid construction, and sequence analysis. Hands on experience in recombinant antibody cloning and production is a plus.

•Familiarity in protein purification, column chromatography and protein characterization procedures such as SDS-PAGE, peptide mapping, Western Blot and ELISA.

•Hands on experience with techniques involved in preclinical in vivo models for oncology is highly desirable.

•Proficiency in application softwares such as MS word, excel, powerpoint, FlowJo, Vector NTI and Graphpad Prism. Ability to independently process and analyze data to deduct valuable scientific conclusions is required.

•Must be organized, self-motivated, ability to multi-task and deliver results in a timely manner to drive projects forward.

•Good communication skills are essential.

Equal Employment Opportunity
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

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Desired Skills and Expertise

Master's Degree

Industry

Pharmaceutical

Experience

5+ years

Job Type

Full Time

Salary / package

Not Specified